Phytoceuticals are plants that have biologically active substances that are pharmacologically / medicinally relevant molecules that produce therapeutic effects (positive health effect). Cumberland Biotherapeutics utilizes natural products (and/or their novel cores) to develop new phytoceutical drug entities, which are highly promising in the area of drug discovery research for alternative healthcare benefits. This includes areas such as Oncology, Dermatology, Rheumatology/ Inflammation, Phyto-cosmetics as alternative healthcare products. Presently, about 25% of medicines are directly derived from nature. About 61% of new chemical entities (NCE) can be traced to a natural product origin. The rapidly evolving recognition is that a significant number of drugs/leads/hits are produced by Mother Nature. It is therefore considered that this area of natural resources should be expanded significantly (Giddings & Newman, 2015a,2015b,2015c; Newman & Cragg, 2016). Accordingly, chemical investigation of natural compounds is one of the most reliable and traditional routes to discover new and novel natural drugs.